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NEST Quality System: Four Core Foundations 1. High-Standard Clean Environment NEST has established a high-standard clean manufacturing system covering life science consumables and medical device pharmaceutical packaging fields. The current cleanroom facilities include: Class 100,000 cleanroom: 10,600 m² Class 10,000 cleanroom: 3,600 m² Injection pen controlled workshop: 2,300 m² Prefillable syringe forming controlled workshop: 850 m² From raw material intake to finished product release, the entire process is strictly controlled under validated conditions. 2. End-to-End Quality System NEST has established a comprehensive quality management system covering R&D, procurement, production, inspection, sterilization, and delivery. The Quality Center is supported by 71 professional quality management personnel. Key Testing Equipment: Malvern Spraytec (UK) spray particle size analyzer Proveris SprayVIEW (USA) spray pattern analysis system ZwickRoell (Germany) universal testing machine Dedicated pharmaceutical packaging testing equipment 3. Global Certifications International Quality Systems: ISO 9001, ISO 13485, ISO 14001, ISO 45001, ISO 14644 Global Market Approvals: EU MDR certification, CE marking MDSAP certification FDA DMF filing, FDA 510(k) registration IVDR-related registrations and approvals Class II medical device registration certificates and manufacturing licenses Pharmaceutical packaging material registration and filing approvals 4. Data Validation System Cell Culture Product Validation: Cell adhesion, cell proliferation, sterility, endotoxin, and cytotoxicity testing Liquid Handling Product Validation: Pipetting accuracy, sealing performance, leakage testing, and centrifugation performance Pharmaceutical Packaging Validation: Biocompatibility, drug compatibility, extractables & leachables, stability, and packaging integrity testing NEST also continuously conducts third-party testing and benchmarking against leading global competitors to ensure that product advantages are supported by robust and reliable data.

On May 15–16, 2026, the 25th China Biologics Products Conference (CBioPC2026) was successfully held at the Nanjing International Expo Center. As a comprehensive life science solutions provider, NEST showcased its core product portfolio and engaged with industry partners to explore the future of biopharmaceutical innovation. During the exhibition, the NEST booth attracted strong visitor interest and active business discussions.   Strong Interest in Pen Injectors & Prefilled Systems NEST presented a comprehensive product portfolio, including reusable pen injectors, cost-effective disposable pen injectors (standard, SP, TSA, and automatic types), RTU supporting products such as cartridges and prefilled syringes, as well as assembly equipment solutions. These products provide safer, more convenient, and patient-friendly self-injection solutions for the biopharmaceutical industry and are widely used for semaglutide, FSH, liraglutide, insulin, growth hormone, and related drugs.   NEST has obtained multiple international certifications, including ISO 9001, ISO 13485, ISO 11137, FDA, and CE certifications, and holds medical device licenses in multiple countries. Production lines operate under GMP standards with third-party monitoring throughout the entire process to ensure compliance and product quality. Supported by a 2,300 m² high-standard manufacturing facility and two fully automated assembly lines, NEST has achieved flexible automated production across the entire process, from mold design to final packaging, enabling rapid response to customized customer needs. Core Advantages Diverse product portfolio: Multiple pen injector options available to match different drug applications. Precision injection molding: High-accuracy dimensional control ensures excellent product consistency. Product validation & patent risk mitigation: Full FTO analysis completed for China, the U.S., the U.K., and Europe. Comprehensive validation reports are available, with designs optimized to reduce patent risks and comply with international standards. Customization services: Appearance, color, dosage, graduation marks, and other features can be customized according to customer requirements.   Closed System & Laboratory Consumables Closed system solutions: Provide sterile protection solutions for the entire biopharmaceutical workflow, from R&D to production, ensuring the integrity and safety of samples and reagents during storage and transfer. Standard laboratory consumables: Covering cell culture, molecular biology, and general laboratory consumables, NEST products are trusted by laboratories worldwide for their reliable quality and cost-effectiveness.   Many long-term customers visited the NEST booth to learn about new products and discuss annual cooperation opportunities, while new visitors gained a deeper understanding of the NEST vision of “developing high-end consumables and building an internationally recognized brand.” Thank you to everyone who visited the NEST booth, and to all partners who choose and trust NEST. We look forward to seeing you again at the next event!

  In the era of biologics, global regulatory capability is your core competitive advantage. With explosive growth in GLP‑1, insulin, growth hormone, and other biologics, safety and compliance standards for drug delivery systems are rising fast. NEST delivers a full‑chain solution built on "High Standards, Strong Compliance, Global Reach." Core Capabilities 1️⃣ Integrated R&D & Manufacturing: In‑house core structure development, mold design, and automated production — with full customization (appearance, dosage, scale markings). 2️⃣ Full Product Coverage: Disposable/reusable pen injectors, prefilled autoinjectors, ready‑to‑use cartridges, COP/COC syringes, nasal spray devices — compatible with GLP‑1, insulin, and more. 3️⃣ Consistent Quality: Automated assembly + standardized processes meet the highest standards for drug-device integration. 4️⃣ Patent Safety: FTO analyses completed for China, US, and Europe — systematically mitigating international patent risks. 5️⃣ Supporting Equipment: Filling & stoppering systems, standalone stopper machines — full support from process development to production. Global Certifications as a Moat ✅ FDA 510(k): K240961 | K240774 ✅ EU MDR Certified ✅ MDSAP (US, Canada, Australia, Japan, Brazil) ✅ 6 U.S. DMF Filings (40744 / 42439 / 40629 / 40922 / 40745 / 38260) ✅ CDE Linked Reviews (including I‑to‑A status) + China Class II Medical Device Registration Global Footprint ? Registration and certification network covering China, the US, Canada, the EU, Southeast Asia, and South America — delivering stable, efficient, and sustainable supply chain support to pharma partners worldwide. Moving forward, NEST will continue to deepen capabilities in pen injectors and autoinjection systems, advancing quality systems and international registrations to provide safer, more efficient, and more reliable drug delivery solutions for the global biopharmaceutical industry. ? ? ?

? Global Research Community Validates NEST Quality: 5,361 SCI Citations Reflect Consistency, Stability, and Scientific Value ? As life science research continues to advance toward higher quality standards, the credibility and reliability of research outcomes have become key indicators of product value. SCI citations remain one of the strongest validations of scientific recognition.As a leading integrated supplier in the life sciences industry, ✔️ NEST has been cited in 5,361 SCI publications as of May 2026. ✔️ In the first quarter of 2026 alone, NEST products were cited in 213 new SCI papers, ✔️ with the highest impact factor reaching 45.8, including continued citations in top-tier journals such as Cell and Science.? These achievements reflect the global research community’s recognition of NEST product quality, stability, and scientific value. The continuous growth in annual SCI citations also highlights the long-term trust and support from researchers and customers worldwide.? Recognition from Top Journals | Selected High-Impact PublicationsThe publication of an SCI paper often represents months or even years of repeated validation. The stability, cleanliness, and batch consistency of laboratory consumables directly affect the reliability and reproducibility of experimental results.话题标签

Cell Passaging Cheat Sheet: Just Copy & Paste ✅Still failing at cell passaging? One diagram to nail it every time ?Calling all cell culture researchers!!Over-trypsinization, poor cell adhesion, confusing split ratios, contamination wiping out your entire flask... I've been there ?This diagram breaks down everything from principles → detailed workflow → pro troubleshooting tips:⏱️ Digestion time: shorter is safer → Over-trypsinization directly slashes cell viability? PBS wash must be thorough → Serum residue = trypsin inactivation? Split ratio depends on cell type → HEK293: 1:3 to 1:6 | Primary cells: 1:2 to 1:3? Don't max out centrifuge speed → 1000 rpm is enough; higher damages cells?️ Aseptic technique is non-negotiable → Every second the lid is open = contamination riskAll parameters are labeled. Literally just copy this.? Save this post, print it for your biosafety hood, and glance at it before every passage. It'll save you years of trial and error ? 话题标签

In May 2026, with the implementation of State Council Decrees No. 818 and No. 828, China’s cell therapy industry is entering a more standardized and system-driven stage. Regulatory focus is shifting from “encouraging innovation” to balancing innovation with safety, upgrading from partial rules to comprehensive governance. Policy highlights: Decree 818 (manufacturing): Strengthens GMP and full-process quality control, emphasizing “controllability.” Decree 828 (regulation): Enhances lifecycle supervision and traceability, emphasizing “traceability.” Industry impact: Laboratory consumables are being redefined with higher entry thresholds. Suppliers are now expected to provide biocompatibility and extractables data, ensure full batch traceability, and meet increased audit requirements. Overall, these policies are driving the industry from a manufacturing-focused model toward a quality system–driven approach, accelerating the shift to higher standards, stronger validation, and stricter compliance. 1. NEST TriSteri™ Ultra-Low Particulate Products Under increasingly stringent regulatory and quality requirements, NEST has launched TriSteri™ ultra-low particulate product line, designed for high-cleanliness applications such as cell and gene therapy, providing reliable consumable solutions for advanced biopharma and research. Applications (GMP-critical processes): Suitable for large-scale cell culture, aseptic bulk filling, API sampling, formulation filling, and high-cleanliness reagent transfer. Key advantages: Ultra-low particulate control: Tested per Chinese Pharmacopoeia (light obscuration method); results significantly below limits, reducing contamination risk. Strict quality inspection: Dual visual inspections ensure no visible particles. Certified quality system: Sterility level SAL 10⁻⁶; free from DNase/RNase, endotoxins, and cytotoxicity; compliant with ISO 13485 and ISO 9001. Triple-layer packaging: GMP-compliant design to prevent contamination and enhance aseptic operation safety. Validation & compliance: Systematic testing supports high standards for biopharmaceutical production and research accuracy. 2. “Hard Requirements” for Laboratory Consumables With evolving regulations, lab consumables must meet not just single performance metrics, but a comprehensive system of capabilities: raw material safety, GMP-level manufacturing, sterility assurance, and data integrity—areas where many companies still face gaps. 01 High-quality raw materials Medical-grade materials compliant with USP Class VI ensure defined composition, stability, and no animal-derived components, reducing risks of cytotoxicity, extractables, and variability. 02 GMP manufacturing & automation GMP-compliant cleanrooms and advanced automated equipment (e.g., ASB systems) enable standardized processes from raw materials to delivery, minimizing contamination and ensuring batch consistency. 03 Sterility assurance In-house sterilization center equipped with IBA Rhodotron® accelerators ensures SAL 10⁻⁶, meeting FDA requirements with stable and effective sterilization control. 04 Third-party validation Comprehensive testing, including biocompatibility, cytotoxicity, and extractables/leachables, supported by complete validation and audit documentation—shifting from “claimed safety” to “proven safety.” 05 Full traceability Upgraded packaging and data systems with QR-coded COA/COC enable batch traceability, supporting audits, compliance checks, and integration with customer quality systems. 3. Integrated Product Portfolio With over a decade of experience in life sciences, NEST has expanded from laboratory consumables to medical devices, pharmaceutical packaging, biobanking solutions, and bioprocess components—driven by continuous innovation and a commitment to high-end consumables. 01 Laboratory consumables Covering cell culture, microbiology, molecular biology, and bioprocessing, NEST products are made from high-quality materials with precision molds and fully automated production, ensuring sterility, non-pyrogenicity, and non-cytotoxicity. A wide range of specifications supports diverse experimental needs. 02 Pharmaceutical packaging Includes disposable pen injectors, prefilled automatic pen injectors, TSA pen injectors, pen injectors, and ready-to-use (RTU) solutions. The implementation of Decrees 818 and 828 is not a constraint, but a shift toward rebuilding industry trust. Future competition will depend on product stability, system robustness, and data reliability. NEST remains committed to high-standard materials, advanced manufacturing, strict sterility assurance, and comprehensive validation—delivering reliable, verifiable quality in an evolving regulatory landscape.  

On April 15, 2026, NEST successfully held its first Japan Distributor Conference in Japan. The event marks an important milestone in NEST’s continued expansion and commitment to the Japanese market.  NEST Successfully Hosts First Japan Distributor Conference at InterContinental Tokyo Bay On April 15, 2026, NEST successfully held its first Japan Distributor Conference at InterContinental Tokyo Bay. The event brought together 13 key distributors and 25 industry representatives from across Japan, marking NEST’s first structured channel meeting in the Japanese market. In the opening speech, Chairman Mr. Yang outlined NEST’s global development strategy and the strategic importance of Japan, providing clear direction and strengthening partner confidence. 1. Japan market NEST has established a subsidiary in Tokyo and set up a local warehouse of approximately 100 m², forming a basic integrated operation system covering sales, storage, and service. Through continuous participation in local industry exhibitions and events, brand awareness in Japan continues to grow. Japan is widely recognized as a high-end benchmark market in life sciences and pharmaceutical packaging, with strong technological leadership and industry standards. 2. Strategic significance NEST has achieved alignment across branding, strategy, and execution, evolving from a traditional distributor model to a long-term strategic partnership. 3. Global footprint NEST products now cover North America, Europe, Southeast Asia, the Middle East, Japan, South Korea, and India. With a “global manufacturing + local warehousing + regional service” model, NEST continues to improve delivery efficiency and supply chain stability, transitioning toward a truly global operating system. 4. Corporate Strength: Dual-Driven by Manufacturing System and Quality Standards NEST Life Sciences (Wuxi) Co., Ltd. was founded in 2009 and has been dedicated to life science and medical consumables, building a global high-end brand. Manufacturing capabilities The company operates a modern production base of approximately 27,000 m², including 10,600 m² Class 100,000 cleanroom, 3,600 m² Class 10,000 cleanroom, 2,300 m² injection pen controlled workshop, and 850 m² prefilled syringe molding area, enabling a fully integrated workflow from raw materials to final delivery. Technology capabilities NEST has introduced advanced ASB one-step injection stretch blow molding systems and Rhodotron TT300 electron beam sterilization equipment, ensuring high product quality and stable sterilization processes. Medical-grade raw materials compliant with USP Class VI are used under GMP standards. Quality system Certified with ISO 9001, ISO 13485, ISO 11137, FDA, CE, and other international standards, NEST fully implements GMP requirements to ensure global consistency and compliance. Product portfolio and services NEST offers a comprehensive range covering lab consumables, medical devices, pharmaceutical packaging, and biotech reagents, serving key fields such as drug development, vaccine production, cell therapy, and IVD. Through continuous supply chain and process optimization, NEST shortens delivery cycles and improves customization capabilities, while building a global localized service network to provide end-to-end support from product selection to technical application and training. With Japan as a strategic hub, NEST advances toward a higher level of global expansion The successful launch of NEST’s first Japan Distributor Conference marks a key milestone in its globalization journey and signals a more mature phase of overseas development. Against the backdrop of continuous advancement in the global life sciences industry, NEST is steadily transitioning from “Made in China” to a truly global brand.

With increasing industry requirements for cartridges, NEST conducted systematic comparative testing across key performance indicators, including appearance and dimensions, silicone oil control, biological performance, and critical physical properties.Core Advantages of NEST Cartridges✔️ NEST cartridges are produced on fully automated lines in partially Class 100 clean environments, with a systematic redesign covering materials, processes, and sterilization.1️⃣ Sterilization Process: One of the first in China to use moist heat sterilizationCompared with traditional ethylene oxide sterilization, moist heat offers more complete and safer sterilization:0 dead space ·0 residue · 0 contaminants · 0 riskUnlike EO, which struggles to penetrate gaps between the cap and body, moist heat ensures more thorough sterilization.2️⃣ Siliconization Process: In-house cross-linked siliconization for higher safety and durabilityA proprietary cross-linked siliconization forms a uniform and stable coating on the inner wall while effectively removing pyrogens.3️⃣ Molding Process: Superior dimensional stability as a fundamental strengthMade from selected imported borosilicate glass tubing and advanced precision molding equipment, ensuring consistent dimensional stability and product uniformity.This study evaluated NEST and three competitor cartridges across 17 key indicators, covering dimensional accuracy, appearance quality, physicochemical performance, biosafety, and functional compatibility.? Overall Conclusion: NEST cartridges demonstrate balanced and excellent overall performance. Key indicators are leading or comparable to competitors, with stable and controllable quality, fully meeting the requirements of automated production lines and clinical applications.话题标签

NEST conducted systematic performance validation on cell culture products, using mainstream “ultra-hydrophilic” products as benchmarks. The comparison was evaluated based on the following key indicators: Surface hydrophilicity (contact angle) Cell culture performance (morphology, viability, proliferation capacity) Surface flatness 01 Core Performance Validation | Key Indicator Analysis 1. Contact Angle — the smaller the value, the better the hydrophilicity Test Result:NEST products maintain a stable contact angle of around 15°, significantly lower than competing products, indicating superior surface hydrophilicity that promotes rapid cell adhesion and stable growth. 2. Cell Culture Performance (1) Cell Morphology Conclusion: Cells exhibit healthy morphology and a stable culture environment, with more uniform performance compared to competitors. (2) Cell Viability Conclusion: NEST products demonstrate better cell viability, consistently slightly higher than competing ultra-hydrophilic products. (3) Cell Proliferation Rate Conclusion: NEST shows a clear advantage in proliferation efficiency, helping shorten culture cycles and improve productivity. (4) Cell Detachment Time Moderate and consistent detachment time → uniform surface treatment and stable cell condition Excessive or highly variable time → may indicate over-adhesion Conclusion: NEST cell culture flasks show slightly shorter detachment times than competitors; both products perform similarly in cell factory applications and meet large-scale culture requirements. 3. Surface Flatness — the structural basis for culture consistency Flatness refers to the geometric uniformity of the culture surface, typically expressed as maximum height deviation: Smaller value → smoother surface Conclusion: NEST offers superior surface flatness, ensuring consistency in large-area cell culture. NEST cell culture products not only demonstrate excellent surface hydrophilicity, but also deliver more stable overall performance in cell condition, proliferation capacity, structural flatness, and operational consistency—outperforming competing ultra-hydrophilic products.

From March 19–21, NEST had the pleasure of participating in the APC Owner Summit 2026, held at the AT&T Hotel and Conference Center. This year’s summit brought together industry leaders and innovators to explore key trends shaping the future of compounding pharmacies, including: The integration of AI in pharmacy operations The growing impact of GLP-1 therapies on the compounding sector At the event, NEST showcased our latest solutions, including pen injectors, filling machines, and integrated delivery systems designed to support safe, efficient, and scalable pharmaceutical production. It was a valuable opportunity to connect with partners, exchange insights, and better understand the evolving needs of the global market. We are inspired by the dynamic discussions and look forward to contributing further to innovation in drug delivery and pharmaceutical manufacturing. Thank you to everyone who visited our booth — we look forward to continuing the conversation. #NEST #APCSummit2026 #PharmaInnovation #DrugDelivery #GLP1 #AIinHealthcare #CompoundingPharmacy

 NEST Pharmaceutical Packaging Product Portfolio Pen Injectors NEST offers reusable pen injectors as well as cost-effective disposable options (standard, SP version, screw-type pens, auto-injectors, etc.). Glass Series NEST’s glass packaging products include RTU cartridges and prefilled nasal spray systems. Key Advantages: Dual sealing structure design High-cleanliness production environment Lubrication, siliconization, and sterilization processes 100% visual inspection COP/COC Series Includes prefilled vials and prefilled syringes. Advantages of COP materials: High transparency Low protein adsorption Excellent chemical stability Strong impact resistance 03 Ensuring Safety from the Source I. Premium Imported Raw Materials NEST uses high-quality imported materials to ensure stable performance in: Biocompatibility Chemical stability Low extractables risk Drug compatibility This minimizes material risks at the source and provides a solid foundation for drug safety. II. High-Grade Cleanroom Manufacturing To ensure product quality, NEST has established a comprehensive clean manufacturing system: 10,600 m² Class 100,000 cleanroom 3,600 m² Class 10,000 cleanroom 2,300 m² dedicated pen injector workshop All production processes are carried out in strictly controlled environments to effectively minimize particles, microorganisms, and contamination risks. III. Full-Process Quality Monitoring During manufacturing, NEST ensures product consistency through multiple quality control measures, including: Automated production equipment In-line quality monitoring systems Full traceability throughout the process 360°control with 100% inspection A systematic quality management approach ensures every product meets strict standards. IV. International Certification System NEST has established a comprehensive compliance and certification system, including: ISO 9001, ISO 13485, ISO 11137 CDE registration China Class II medical device registration FDA registration US DMF Multiple international medical device certifications Production strictly follows GMP standards and is verified by third-party testing institutions. NEST consistently upholds: Compliance as the foundation Quality as the core Safety as the baseline Providing global biopharmaceutical companies with safe, stable, and reliable pharmaceutical packaging solutions.

BIOCHINA 2026 has come to a successful close! As an exhibitor, NEST showcased a range of innovative products and attracted strong attention at the event. ? Featured Product in the Spotlight ? Closed System – A key highlight of the exhibition, drawing significant interest from visitors. NEST’s Closed System is designed for biopharmaceutical processes and is ready to use, helping reduce the risk of contamination during drug development and manufacturing, while ensuring product safety.Key advantages:✔️ Time-saving and efficient: Reduces time spent on tubing design, assembly, and sterilization, improving production efficiency✔️ Flexible configuration: Various containers and transfer caps available to meet different process requirements✔️ Customization: Tailored solutions based on specific customer needs and production scenarios? Pen Injectors — Innovative Solutions for Precise Drug DeliveryAt BIOCHINA 2026, NEST Biotechnology showcased its latest products and solutions, including pen injectors and prefilled syringe components. Our professional team introduced the products, supporting certifications, and comprehensive solutions, demonstrating NEST’s strong capabilities in the pharmaceutical packaging field.Key advantages:✔️ Diverse product specifications: A wide range of options available to match different drug formulations✔️ Precision injection molding: High-precision dimensional control ensures product consistency✔️ Product validation & FTO analysis: Completed FTO analysis in China, the U.S., the U.K., and Europe, with full validation reports and patent risk avoidance design✔️ Customization services: Appe v arance, color, dosage, and scale markings can be tailored according to customer requirements? Moving Forward Together, Creating the Future ? Looking ahead, NEST will continue to uphold the principles of innovation, quality, and service, focusing on the life sciences field and providing high-quality products and solutions for aresearchers and biopharmaceutical companies worldwide. ? ? ? 话题标

With the full operation of the NEST Biotechnology Industrial Park, NEST has further upgraded its capabilities in high-end plastic container manufacturing. To enhance product quality and production capacity, NEST has introduced internationally advanced ASB one-step four-station Injection Stretch Blow Molding equipment, representing the cutting-edge level of global ISBM container manufacturing.     01 One-Step Process for High-Quality Containers The newly introduced equipment adopts a one-step, four-station Injection Stretch Blow Molding (ISBM) process, enabling the entire production cycle—from raw material to finished container—to be completed on a single machine. This highly integrated process reduces intermediate steps while significantly improving production stability and cleanliness. The system can also design the preform structure based on the final container dimensions, precisely controlling the stretch ratio to achieve more uniform wall thickness and enhanced clarity of the finished container. 02 Key Advantages The equipment upgrade brings comprehensive improvements to product performance: More stable product quality Higher product cleanliness Improved container structural performance Greater consistency and large-scale production capability Enhanced appearance and transparency 03 Key Technology Highlight — Zero Cooling Technology The system is equipped with advanced Zero Cooling Technology, which uses a precise temperature control system to maintain uniform temperature distribution during the molding process. This technology further optimizes the stretch ratio and ensures more uniform wall thickness, significantly enhancing container strength and product stability. 04 Strategic Significance of the Equipment Upgrade The introduction of this advanced equipment further strengthens NEST’s manufacturing capabilities, enhances product quality advantages, improves large-scale production capacity, and supports expansion into high-end application markets, driving the company’s long-term development. The introduction of advanced equipment marks another important step in strengthening NEST’s manufacturing capabilities. Looking ahead, NEST will continue to enhance product quality, production efficiency, and manufacturing stability, driving high-end laboratory consumables and container products toward even higher standards.  

One question. Seamless product consultation across website and WeChat. NEST is proud to introduce our new intelligent consultation solution — the NEST AI Smart Assistant, now available on multiple platforms. 01 What is the NEST AI Smart Assistant? The NEST AI Smart Assistant is an AI-powered consultation service built on NEST’s comprehensive product data system. It is now live on both: The NEST Official Website The “NEST Biotechnology” WeChat Subscription Account Just like consulting a professional product specialist, you can ask questions directly and receive clear, accurate answers instantly. 02 Multi-Platform Access — Anytime, Anywhere Website: Visit our official website and click the AI icon on the right side of the page to start chatting. WeChat: Enter the “NEST Biotechnology” subscription account and access the AI consultation feature directly through the chat interface. 03 Comprehensive Product Consultation Capabilities Designed around customers’ key concerns in product selection, application, procurement, and project evaluation, the NEST AI Smart Assistant supports inquiries including but not limited to: Performance Parameters Key specifications, model differences, and application suitability recommendations Product Advantages Design highlights, comparative insights, and fast model selection guidance Specifications & Materials Dimensions, volume capacity, material details, and storage & transportation information Quality & Compliance Shelf life, sterilization methods, and certification systems Ordering Support Model guidance, product images, and application references 04 Why Launch the NEST AI Smart Assistant? The NEST AI Smart Assistant represents a service upgrade built on three core advantages: faster, more accurate, and more convenient support. Instead of searching through pages or waiting for responses, users can now access structured and precise answers 24/7 via our official website and WeChat platform. For communication efficiency: It reduces repetitive inquiries and ensures consistent, professional information — allowing discussions to focus on solutions and decision-making. For service experience: It transforms the process from “passively searching for information” to “actively receiving answers,” building an integrated multi-platform intelligent service system. Looking ahead, the NEST AI Smart Assistant will continue to learn and evolve — expanding coverage across more product lines, application scenarios, and specialized topics, while continuously enhancing the depth of responses and overall service experience.

? 2025 Hot Product Review — NEST Ready-to-Use Cartridges As biologics and injectable drug delivery systems continue to advance, stability, safety, and consistency have become the core concerns for pharmaceutical manufacturers and R&D teams when selecting cartridges. ? 1️⃣ Sterilization Process: Steam-Sterilized Cartridges NEST is the first domestic manufacturer to adopt moist heat (steam) sterilization for cartridges. Compared with conventional ethylene oxide (EO) sterilization, moist heat sterilization provides a more thorough and safer solution, featuring: Zero blind spots · Zero residues · Zero contamination · Zero hidden risks ‼️ Moist heat sterilization demonstrates more effective microbial inactivation within the cartridge structure. 2️⃣ Siliconization Process: In-House Crosslinked Siliconization for Enhanced Safety and Durability NEST uses a proprietary crosslinked siliconization process, in which silicone oil molecules are transformed from a linear structure into a stable three-dimensional network through high-temperature curing. This forms a uniform and firmly bonded siliconized layer on the inner surface of the cartridge while effectively removing pyrogens. This crosslinked siliconized layer delivers four key advantages: ✔️ Enhanced safety: ✔️Long-lasting performance: ✔️Improved compatibility: ✔️Lower drug residue: 3️⃣ Forming Process: Dimensional Stability as a Core Strength NEST cartridges are manufactured from imported medium borosilicate glass tubing, combined with advanced forming equipment and well-controlled processes to ensure dimensional stability and consistency from the source. ‼️ NEST cartridges showed the lowest CV values for both inner and outer diameters among all samples, demonstrating superior dimensional stability. (Lower CV values indicate higher dimensional consistency and stability.)  

Strengthening Compliance, Advancing Toward Global Markets Recently, NEST has officially completed U.S. Food and Drug Administration (FDA) establishment registration and obtained its FDA registration certificate. This achievement marks that NEST has met the basic regulatory entry requirements of the U.S. market for life science and biopharmaceutical-related products, reflecting its robust capabilities in compliance management, quality control, and international operations, and laying a stronger regulatory foundation for serving global customers. The FDA is one of the world’s most influential regulatory authorities for medical products and life sciences. FDA establishment registration is a fundamental compliance filing required for companies engaged in the manufacturing, processing, packaging, or holding of regulated products. What Does FDA Registration Mean for NEST? FDA registration represents a milestone in NEST’s long-term standardized management practices. It confirms that NEST’s corporate entity has been officially recognized by the FDA and listed in its database, ensuring international traceability. It also demonstrates that NEST’s quality management system is aligned with international standards, and that its R&D and manufacturing processes comply with global regulatory expectations—significantly enhancing brand credibility in highly regulated markets such as North America and Europe. What Does This Mean for Customers? Lower compliance risk: Clear corporate registration status and smoother audit and inspection processes More stable supply: FDA registration requires continuous compliance investment, supporting product consistency and long-term supply reliability Easier global expansion: FDA registration is a key advantage in international projects, reducing regulatory communication costs and accelerating global business deployment Scope of FDA Registration and Product Listing This FDA registration and product listing cover multiple core NEST product categories, including but not limited to: Laboratory and clinical consumables: Cell culture flasks, sterile sample containers, centrifugation-related products Cell and microbiology-related products: Media preparation, transportation, and storage products Medical and drug delivery components: Syringe pistons, sterile swabs and absorbent tips, and nasal drug delivery devices Compliance as a Long-Term Commitment Obtaining FDA registration is a significant milestone in NEST’s globalization journey—but not the endpoint. Moving forward, NEST will continue to uphold regulatory compliance as a fundamental principle and product quality as its core focus, delivering stable, reliable, and long-term trusted consumables and solutions for global life science and biopharmaceutical customers. Compliance is NEST’s most basic—and most important—commitment to its customers.

In biopharmaceutical and biologics manufacturing, large-volume liquid materials are involved throughout key processes such as media preparation, process scale-up, intermediate storage, and final product transfer. NEST now introduces the 10 L PC Square Storage Bottle, providing a more reliable solution for production-scale liquid management.       01 Product Overview The NEST 10 L PC Square Storage Bottle is a ready-to-use sterile liquid container specifically designed for pharmaceutical and biologics manufacturing. It is suitable for the aseptic storage, precise formulation, and safe transfer of critical liquids. 02 Product Advantages 1. Medical-grade materials with excellent resistance Manufactured from medical-grade polycarbonate (PC) Non-cytotoxic and animal-origin free Withstands –80 °C cryogenic storage Supports 121 °C / 30 min autoclave sterilization Cap made of PP with a silicone gasket, validated for repeated freeze–thaw cycles and sterilization Stable structure with no deformation or leakage 2. Reliable sterility and regulatory compliance Produced in a Class 100,000 clean environment and sterilized by electron beam, achieving SAL = 10⁻⁶ Pyrogen-free, nuclease-free, and low particulate levels Double heat-sealed sterile packaging, compliant with GMP cleanroom material entry requirements 3. Optimized structural design Narrow-neck design for accurate liquid control Molded sidewall grooves for improved grip and pouring stability Concave bottom design compatible with magnetic stirring Cap with integrated silicone gasket ensures secure sealing and leak prevention     03 Applications Preparation and aseptic storage of media and buffers Storage of critical process intermediates and semi-finished products Closed and safe transfer of process fluids 04 Advanced Manufacturing Technology NEST adopts internationally leading Japanese ASB one-step, four-station injection stretch blow molding (ISBM) fully automated equipment. The 10 L PC Square Reagent Bottle is formed using a one-step four-station ISBM process, integrating injection molding, conditioning, stretch blow molding, and bottle removal within a single enclosed system. From raw material feeding to final demolding, the entire process is conducted under closed and controlled conditions, ensuring high cleanliness, consistency, and product quality.

Driven by the demand for higher sterilization standards, NEST has established a mature, stable, and fully validated irradiation sterilization solution system in collaboration with Futeng’s professional irradiation platform. Futeng has introduced the internationally advanced IBA Rhodotron® TT300 dual-beam accelerator from Belgium, integrating both electron beam and X-ray irradiation technologies. This significantly enhances sterilization capacity, process stability, and product compatibility, providing high-standard, verifiable sterilization solutions for medical devices, biopharmaceuticals, and laboratory products. Rhodotron® TT300 is a high-power model developed by IBA for large-scale industrial irradiation facilities, specifically designed for continuous, high-throughput sterilization applications with tightly controlled doses, balancing efficiency, safety, and process flexibility. The Rhodotron® TT300 uses a dual-beam technology, supporting two mainstream irradiation methods in a single system: electron beam (E-beam) irradiation and X-ray irradiation. By switching modes, it can flexibly accommodate different product characteristics and sterilization process requirements, significantly enhancing the overall service capability of an irradiation facility. 02 Key Advantages Compatible with products of all densities, offering broad application coverage Leading X-ray performance with excellent penetration and uniformity High efficiency and energy-saving, with outstanding system cost-effectiveness Industrial-grade reliability, suitable for long-term continuous operation Dual assurance of compliance and dose control 03 Application Areas Medical devices and single-use consumables Biopharmaceutical and laboratory-related products Aesthetic medicine and health protection products Research and industrial products 04 Significance of Introducing TT300 for NEST Products Improves sterilization consistency and reliability, reducing variation and blind-spot risks Supports high-standard product development and multi-scenario applications Strengthens compliance and facilitates international market access Enhances production capacity and builds customer trust The introduction of Rhodotron® TT300 not only elevates the stability and consistency of NEST product sterilization, but also provides solid support for high-standard product development, international compliance, and reliable supply. Leveraging this advanced in-house sterilization capability, NEST continues to reinforce its quality barriers, ensuring long-term product safety and reliability, while delivering greater trust and value to customers and partners.

1️⃣ELISA plates, also known as enzyme-linked immunosorbent assay (ELISA) plates, are widely used laboratory tools in biology, medicine, food testing, and related fields. They are primarily designed for the detection of antibodies, antigens, proteins, and other analytes in liquid samples. From disease diagnostics to food safety testing, ELISA plates play an indispensable role in modern analytical applications. 2️⃣Structure and Types of ELISA Plates ELISA plates typically consist of 96 individual wells, with each well used for sample addition and detection. The most common format is the 96-well plate, while 384-well or higher-density formats are used for high-throughput applications. The wells are generally made of plastic, most commonly polystyrene, to ensure efficient adsorption and reliable interactions between samples and reagents. 3️⃣How to Choose the Right ELISA Plate 01 Depending on the detection method, ELISA plates are available in different colors. NEST currently offers clear, white, and black ELISA plates. ▶Clear plates: mainly used for absorbance (optical density) measurements ▶White plates: mainly used for chemiluminescence and colorimetric substrate detection ▶Black plates: mainly used for fluorescence detection 02 Detachable vs. Non-detachable Plates 4️⃣ How to Use ELISA Plates–Key Tips Sample Addition Mixing and Incubation Bubble and Contamination Prevention Plate Handling Washing Detection and Analysis Error Control    

? NEST 2025 Highlights A Year of Steady Progress and Continuous Growth ? ✔️ Launched multiple new products, expanding our laboratory product portfolio ✔️ Several products obtained Class II medical device certification ✔️ Upgraded and optimized core products to enhance user experience ✔️ Actively participated in industry exhibitions, engaging with customers face to face ✔️ Built a solid foundation for continued growth in 2026 PART 1️⃣ | Innovation — 20+ New Products Launched 01 In 2025, NEST successively launched reusable pen injectors, more cost-effective disposable pen injectors, ready-to-use sterile accessory products, and combination-product assembly equipment, delivering safer, more convenient, and more user-friendly self-injection solutions for the biopharmaceutical industry. 02 NEST expanded its bioprocessing accessory portfolio with large-volume specifications. 03 NEST launched the new T400 Cell Culture Flask. 04 NEST introduced low-binding pipette tips, designed to reduce enzyme or antibody loss, improve experimental accuracy, and minimize sample waste. 05 NEST launched slidable Petri dishes, specifically designed for automated filling systems. PART 2️⃣ | Compliance — Advancing Within Standards In 2025, multiple NEST products obtained Class II medical device registrations as well as import medical device approvals in multiple countries. These achievements were officially released through authorized channels, reflecting comprehensive verification of product safety, stability, and regulatory compliance. PART 3️⃣ | Continuous Iteration in Maturity In 2025, NEST upgraded and optimized several mature products: 01 Added COA QR codes to product packaging, enhancing overall packaging services. 02 Upgraded GelNest Organoid V3, NEST’s third-generation large-scale model. 03 Added maximum freezing position indicators to NEST centrifuge tubes. 04 Launched narrow-neck versions of NEST round reagent bottles. PART 4️⃣ | On Site — Engaging with the Industry Throughout the year, NEST actively participated in 30+ industry exhibitions and professional meetings, connecting face-to-face with partners and customers across different cities and scenarios. PART 5️⃣ | 2026 — We Are On The Way In 2026, new product planning and development will continue steadily across pre-filled syringes, general accessories, closed systems, and routine consumables. With a stronger foundation, NEST is ready to enter a new stage of growth in 2026. ?